Topical clobetasol for the treatment of toxic epidermal necrolysis: study protocol for a randomized controlled trial

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Topical clobetasol for the treatment of toxic epidermal necrolysis: study protocol for a randomized controlled trial

BACKGROUND Toxic epidermal necrolysis (TEN) is a rare systemic allergic drug eruption with high patient mortality. Currently, no established treatments have been shown to be effective for TEN beyond supportive care. Prior studies of systemic corticosteroids have yielded conflicting data, with some showing a possible benefit and others reporting in increased mortality. However, topical steroids ...

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Topical Ophthalmic Cyclosporine in the Treatment of Toxic Epidermal Necrolysis

Aim. To describe a case of toxic epidermal necrolysis (TEN) with ocular involvement treated with topical ophthalmic cyclosporine. Case Presentation. A 20-year-old woman developed TEN following administration of carbamazepine that was prescribed for epilepsy. Ophthalmic examination revealed bilateral pseudomembranous conjunctivitis. She was hospitalized in the intensive care unit and treated wit...

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study of cohesive devices in the textbook of english for the students of apsychology by rastegarpour

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comparison of topical nifedipine with oral nifedipine for treatment of anal fissure: a randomized controlled trial

background medical sphincterotomy has gained popularity as a treatment for anal fissure. calcium channel blockers in topical forms could also be appropriate with low adverse effects. objectives this was a prospective randomized controlled trial to compare topical and oral nifedipine in the treatment of chronic anal fissure. patients and methods a prospective randomized controlled trial was cond...

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ژورنال

عنوان ژورنال: Trials

سال: 2015

ISSN: 1745-6215

DOI: 10.1186/s13063-015-0879-7